- Translational research using emerging targeted agents
- Clinical trials for breast cancer and early phase clinical trials
- DNA damage repair

1997.03 ~ 1998.09 Research Fellow at Division of Internal Medicine,Department of Neuro-Oncology, M.D. Anderson Cancer Center, Houston, Texas, USA
1998.10. ~ 2003.08.Clinical Research Fellow & Research Associate & Instructor, Assistant Professor, Department of Internal Medicine, Ewha Womans University, College of Medicine, Seoul, Korea
2003.09. ~ Present Assistant Professor, Associate Professor, Professor, Department of Internal Medicine, Seoul National University, College of Medicine
2008.03 ~ 2009.02 Translational Research Scientist, AstraZeneca Oncology R&D Center, Cheshire, UK
2010.02 ~ Present Board of Directors, Korean Cell Line Bank
2015.03. ~ 2022.02. Director of Breast Cancer Committee, Director of External Cooperation Committee, Korean Cancer Study Group (KCSG)
2014.05 ~ 2023.11. Chair for External Cooperation Committee, Scientific Committee, Organizing Committee, Korean Society of Medical Oncology (KSMO)
2019.06. ~ Present Director, Cancer Research Institute, Seoul National University
2020.06. ~ Present Director of International Affairs Committee, Korean Cancer Association (KCA)
2021.03. ~ Present Board of Directors, Translation Research in Oncology (TRIO)

2020 Boryung Award for Cancer Research from Korea Cancer Research Foundation
2023 Outstanding Research Achievement from Seoul National University college of Medicine
2023 Wunsch Medical Award from Korean Academy of Medical Sciences